静电纺丝法制备抑菌性聚酰亚胺纳米纤维

Preparation of Polyimide Nanofiber with Antimicrobial Activity by Electrospinning

采用静电纺丝技术,以联苯四甲酸二酐(BPDA)和4,4'-二氨基二苯醚(ODA)为单体,硝酸银为银源,通过两步法制备含银聚酰亚胺(PI/Ag)纳米纤维.通过X射线衍射(XRD)、透射电子显微镜(TEM)及扫描电子显微镜(SEM)表征了PI/Ag纳米纤维的结构和微观形貌;通过浸渍培养法研究了聚酰亚胺(PI)及PI/Ag纳米纤维的抑菌性能.结果表明,聚酰亚胺基体中存在单质银的立方晶体结构,银粒子在聚酰亚胺基体表面均匀分散,平均粒径为10 nm;PI/Ag纳米纤维对大肠杆菌(E.coli)、金黄色葡萄球菌(S.aureus)和枯草芽孢杆菌(B.subtilis)表现出良好的抑菌效果,最大抑菌率可达99.1%,为聚酰亚胺在耐高温抑菌生物医用材料等领域的应用提供了新的方向.

3,3＇,4,4＇-Biphenyl tetra carboxylic diandhydride,4,4＇-oxydianiline and Ag NO3 were used to synthesis polyimide nanofiber with silver through two steps by electrospinning. The structure and morphology of nanofibers were studied by X-ray diffraction（ XRD）,transmission electron microscope（ TEM） and scanning electron microscopy（ SEM）. The antimicrobial activity of polyimide（ PI） and polyimide containing silver（ PI/Ag） were researched through impregnation method. The results showed that silver＇s crystal structure appeared in polyimide matrix,and silver particles,which average diameters were about 10 nm,dispersed uniformly on polyimide surface. The antimicrobial activities of PI / Ag nanofiber against E. coli,S. aureus and B. subtilis illustrated excellent effect and the best antibacterial rate up to 99. 1%. This study may provide a new insight for polyimide applied in biomedical materials and other applications with good thermal performance and antibacterial property.