眩晕康汤联合倍他司汀治疗无痛性心绞痛99例

XuanYun Kang Decoction Combined with Betahistine in Treating 99 Cases of Stable Angina Pectoris

目的:观察眩晕康汤联合倍他司汀治疗气虚血瘀型无痛性心绞痛的临床疗效。方法:将198例患者随机分为观察组与对照组各99例,2组均给予常规基础治疗,对照组在此基础上给予倍他司汀治疗,治疗组给予眩晕康汤联合倍他司汀治疗,2组均治疗14天。结果:总有效率观察组、对照组分别为94.9%、84.8%,临床疗效观察组优于对照组(P<0.05)。左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)及超敏C-反应蛋白,肌钙蛋白(c Tn I)值2组治疗后均明显下降,观察组下降更明显,2组比较差异有统计学意义(P<0.05)。治疗期间上腹部不适、反酸、纳差、肝功能损害等并发症发生率观察组明显低于对照组(P<0.05)。结论:眩晕康汤联合倍他司汀治疗气虚血瘀型无痛性心绞痛能有效改善心功能,降低炎症因子的表达,安全性较好。

Objective： To observe clinical effects of XuanYunKang decoction jointed with betahistine in treating stable angina pectoris. Methods： All 198 patients were randomized into the observation group and the control group, 99 cases each group, both groups accepted routine treatment, the control group were treated by betahistine,the treatment group received XuanYunKang decoction and betahistine, both groups were treated for 14 days. Results：Total effective rates of the observation group and the control group were 94.9% and 84.8% respectively, the observation group was superior to the control group in clinical effects（P〈0.05）. The levels of LVEDD, LVESD, hs CRP and c Tn I decreased obviously after treating（P〈0.05）, the decrease of the observation group was more obvious（P〈0.05）.The observation group was significantly lower than the control group in the incidences of the complications including discomforts in the upper abdomen, sour regurgitation, poor appetite, liver function damage and others（P〈0.05）.Conclusion： XuanYunKang decoction jointed with betahistine in treating stable angina pectoris could effectively improve heart function and decrease the expressions of inflammatory factors with high safety.