丹红注射液联合多索茶碱注射液治疗慢性肺心病60例

Treating 60 Patients with Chronic Pulmonary Heart Disease by DanHong Injection and Doxofylline Injection

目的:观察丹红注射液联合多索茶碱注射液治疗慢性肺心病的临床疗效。方法:将120例患者随机分为观察组、对照组各60例,2组均给予常规治疗,对照组同时加用多索茶碱注射液治疗,观察组在对照组治疗基础上加用丹红注射液治疗,2组均连续治疗14天。结果:总有效率观察组为98.3%,对照组为88.3%,临床疗效观察组优于对照组(P<0.05)。左室射血分数(LVEF)和左室舒张末径(LVDD)值治疗后2组均明显上升(P<0.05),而左室收缩末径(LVSD)值2组均明显下降(P<0.05);LVEF、LVDD和LVSD值治疗后2组比较,差异有统计学意义(P<0.05)。证候积分治疗后2组均明显下降(P<0.05),观察组较对照组降低更明显(P<0.05)。生活质量评分和6分钟步行试验观察组均高于对照组(P<0.05)。结论:丹红注射液联合多索茶碱注射液治疗慢性肺心病能缓解临床症状,从而提高临床疗效,提高生活质量。

Objective： To survey curative effects of DanHong injection combined with doxofylline injection in treating chronic pulmonary heart disease. Methods： Altogether 120 patients were randomly allocated to the observation group and the control group, 60 cases each group, both groups accepted routine treatment, the control group were treated with doxofylline injection simultaneously, the observation group received DanHong injection on the basis of the therapy the control group accepted, both groups were treated for 14 days consecutively. Results： Total effective rate of the observation group was 98.3%, higher than 88.3% of the control group, the observation group was superior to the control group in clinical effects（P〈0.05）. LVEF and LVDD in both groups rose remarkably after treating（P〈0.05）, while LVSD decreased notably in both groups（P〈0.05）; the difference showed statistical meaning in the comparison of LVEF, LVDD and LVSD after treating between both groups（P〈0.05）. Symptom integrals lowered notably in both groups after treating（P〈0.05）, the observation group was more notable than the control group in the decrease（P〈0.05）. The observation group was higher than the control group in life quality scales and six minutes walking test（P〈0.05）. Conclusion： DanHong injection combined with doxofylline injection in treating chronic pulmonary heart disease could alleviate clinical symptoms, therefore to improve clinical effects and quality of life.