盐酸氨溴索治疗新生儿感染性肺炎的疗效观察

Curative Effect Observation of Treating Neonatal Lnfectious Pneumonia with Ambroxol Hydrochloride

目的:探讨新生儿感染性肺炎采用盐酸氨溴索治疗的临床效果。方法:入选某院符合标准的感染性肺炎患儿94例,按照治疗方式的不同分为治疗组和对照组,每组47例。对照组患儿实施常规治疗,治疗组在对照组的基础上实施盐酸氨溴索雾化吸入治疗,观察两组患儿治疗后的临床效果、症状改善等情况。结果:两组患儿治疗后,病情均有改善,但治疗组患儿的氧疗时间、住院时间、呼吸困难改善时间及吸痰次数均显著优于对照组患者,治疗组患者的总有效率为89.4%显著优于对照组的61.7%,治疗组患儿的PaO_2和PaCO_2指标改善情况显著优于对照组,结果具有统计学差异(P<0.05)。结论:盐酸氨溴索治疗新生儿感染性肺炎,效果显著,值得推广应用。

Objective:To explore the clinical effect of treating neonatal infectious pneumonia with ambroxol hydrochloride.Methods:94neonates with infectious pneumonia in a hospital were selected and divided into treatment group and control group according to different therapies,47 cases in each group.The control group adopted the conventional therapy;the treatment group adopted the aerosol inhalation of ambroxol hydrochloride on the basis of the treatment of the control group.After treatment,the clinical effect and improvement of symptoms of two groups were observed.Results:After treatment,the symptoms of two groups were improved.The time of oxygen therapy,hospitalization time,time of improving the dyspnea and times of sputum suction of treatment group were significantly better than those of control group.The total effective rate of treatment group(89.4%)was significantly higher than that of control group(61.7%);improvement of PaO_2 and PaCO_2 of treatment group was significantly better than that of control group(P<0.05).Conclusion:Ambroxol hydrochloride has an obvious effect in the treatment of infectious pneumonia for neonates,it is worthy of clinical promotion and application.