重组牛碱性成纤维细胞生长因子联合康复新液治疗新生儿尿布皮炎的效果观察

Effect of recombinant bovine basic fibroblast growth factors combined with new rehabilitative liquid on neonatal diaper dermatitis

目的探讨重组牛碱性成纤维细胞生长因子联合康复新液治疗新生儿尿布皮炎的效果。方法选择2013年8月~2014年7月本院儿科住院的新生儿尿布皮炎患儿120例,采用随机数字表法分为对照组和观察组,每组各60例,对照组患儿采用常规护理,观察组患儿使用重组牛碱性成纤维细胞生长因子联合康复新液护理。比较两组患儿的治疗总有效率和愈合时间。结果观察组患儿治疗总有效率为95.00%,对照组患儿治疗总有效率为70.00%,两组比较,差异有统计学意义（P〈0.05）。观察组患儿愈合时间（4.00±0.82）d,对照组患儿愈合时间（6.00±1.64）d,两组比较,差异有统计学意义（P〈0.05）。结论重组牛碱性成纤维细胞生长因子联合康复新液治疗新生儿尿布皮炎疗效显著,减少愈合时间,值得在临床推广和应用。

Objective To investigate the effects of recombinant bovine basic fibroblast growth factors combined with new rehabilitative liquid on neonatal diaper dermatitis. Methods One hundred and twenty neotates with neonatal diaper dermatitis from August 2013 to July 2014 were randomly divided into the control group and experiment group, 60 cases in each group. The control group was treated with conventional care, while the observation group with recombinant bovine basic fibroblast growth factors combined with new rehabilitative liquid. The total effective rate and the treatment time were compared between the two groups. Result The total effective rate of the observation group was significantly higher than that of the control group（P〈0.05） and the treatment time of the observation group was statistically significantly shorter than that of the control group（P〈0.05）. Conclusion Recombinant bovine basic fibroblast growth factors combined with new rehabilitative liquid is effective in the treatment of neonatal diaper dermatitis and it is worth promoting and using clinically.