甲状腺癌患者术后医院感染因素分析及预防措施

The Postoperative Hospital Infection Factors Analysis and Prevention Measures of Thyroid Cancer Patients

目的研究分析甲状腺癌患者术后医院感染因素,并针对以上危险因素采取有效的措施预防,以降低甲状腺癌患者术后围手术期的感染发生率。方法选取该院近4年收治的甲状腺癌术后患者作为研究对象,选取60例术后发生院内感染的患者设为观察组,把60例同期未发生术后感染的患者作为对照组,对两组患者进行单因素和非条件多因素logistic回归分析,寻求导致术后发生院内感染的高危因素。结果单因素分析结果显示,年龄、血糖、肿瘤的病理分型、手术时间、住院时间及术前使用抗菌药情况相比,经检验差异有统计学意义(P<0.05);非条件多因素logistic回归分析结果显示,年龄(β=1.56,OR=3.793)、血糖(β=1.41,OR=3.896)、肿瘤的病理分型(β=1.32,OR=4.143)、手术时间(β=1.44,OR=3.643)、住院时间(β=1.66,OR=3.366)及术前使用抗菌药情况(β=1.34,OR=4.781)是术后患者发生院内感染的高危因素。结论年龄、血糖、肿瘤的病理分型、引流时间、住院时间及术前使用抗菌药情况以上几个因素对甲状腺癌患者术后发生医院感染有着较为显著的影响,临床工作者应加以重视。

Objective To study the postoperative hospital infection factors of thyroid cancer patients and take effective preventive measures, in order to reduce postoperative thyroid cancer patients perioperative infection incidence. Methods 60 postoperative cases with thyroid cancer, which admitted in our hospital nearly four years and nosocomial infection occurred,were selected as the infection group. 60 cases in the same period, there was no postoperative infection of patients selected as control group. The single and unconditioned multivariable factor logistic regression analysis was used in the two groups,in order to find the high risk factors of nosocomial infection. Results The single factor analysis results showed that age,blood glucose, tumor pathology classification, operation time, length of hospital stay, and preoperative use of antimicrobials compared the difference was statistically significant difference（P〈0.05）; unconditioned multiariable logistic regression analysis results showed that age（β=1.56,OR=1.56）, blood sugar（β=1.41, OR=1.41）, tumor pathological classification（β=1.32,OR=4.143）, the operation time（β=1.44,OR=1.44）, length of hospital stay（β=1.66,OR=1.66） and preoperative use of antibacterial drug（β=1.34,OR=1.34） was the risk factors of nosocomial infection in patients with postoperative. Conclusion Several factors such as age, blood glucose, tumor pathology classification, operation time, length of hospital stay, and preoperative use of antimicrobials has a significant effect on postoperative nosocomial infection of patients with thyroid carcinoma, clinical staff should be paying attention.