摘要
目的探究和肱踝脉搏波传导速度(baPWV)与血浆脂蛋白相关磷脂酶A2(LP-PLA2)水平检测在冠心病患者诊断中的应用意义。方法选取2015年1—12月该院怀疑或确诊为冠心病的患者共计156例,按照患者冠状动脉造影(CAG)检测结果,将其分为冠心病组及正常组,再根据患者病变血管支数将其分为单支组(A组),双支组(B组)及多支组(C组),对患者LP-PLA2及baPWV水平进行检测。结果冠心病组患者LP-PLA2水平为(36.61±17.42)μg/L,baPWV为(1 752.18±267.41)cm/s,两者检测结果均高于正常组(P<0.05),C组患者LP-PLA2水平为(48.98±11.42)μg/L,baPWV为(1 897.92±276.14)cm/s,与其他两组相比,差异明显(P<0.05),且A组与B组差异有统计学意义(P<0.05),且B组高于A组。结论机体内baPWV及LP-PLA2水平与冠心病的发生与发展存在密切联系,临床上可通过检测患者baPWV及LP-PLA2水平判断患者是否患有冠心病,并可推测其病情发展程度,以选择合适的治疗方法。
Objective To explore and brachial ankle pulse wave velocity（baPWV） and plasma lipid protein associated phospholipase A2（Lp-PLA2） level detection in the diagnosis of coronary heart disease patients. Methods From January2015 2015 to December in our hospital with confirmed or suspected coronary heart disease patients with a total of 156 cases, according to the test results of the patients with coronary angiography（CAG）, divided into coronary heart disease group and normal group, according to the vascular lesions in patients with count divided into single group（group A）, double vessel group（group B） and multivessel group（Group C）, on patients with Lp-PLA2 and levels of baPWV in Detection. Results In patients with coronary heart disease group of Lp-PLA2 activity for（36.61±17.42） g/L, baPWV for（1 752.18±26.741） cm/s, both test results were higher than normal group（P〈0.05）. Patients in group C of Lp-PLA2 activity for（48.98±11.42）g/L, baPWV for（1897.92±276.14） cm/s, compared with the other two groups, significant difference（P〈0.05）, and between group A and group B also meaningful（P 〈0.05）, and group B than a group. Conclusion The body Ba PWV and Lp-PLA2 levels and severity of coronary heart disease occurrence and development is closely linked, clinical on can is suffering from coronary heart disease by detection of patients with baPWV and Lp-PLA2 levels to determine the patients, and may infer the degree of disease development, to select the appropriate treatment.
出处
《中国卫生产业》
2015年第31期112-114,共3页
China Health Industry
