喜疗妥和水胶体透明贴预防外周静脉化疗致静脉炎的效果比较

Comparison of the effect of MucopolysaccharidePolysulfateCream and hydrocolloid transparent stickers in the prevention of phlebitis caused by chemotherapy via superficial vein indwelling needle

目的探讨喜疗妥药膏和康惠尔水胶体透明贴预防浅静脉留置针化疗所致静脉炎的效果比较。方法采用随机抽样的方法,纳入121例经浅静脉留置针行PVB（顺铂＋长春新碱＋博来霉素）方案化疗的宫颈癌患者,随机分对照组和实验组。在留置针穿刺成功后,对照组在静脉穿刺点及沿静脉走向近心端,覆盖康惠尔水胶体透明贴,并上覆普通透明膜（3M贴）固定留置针;实验组则在穿刺静脉上方先用3M贴固定留置针,后避开穿刺点在近心端呈椭圆状涂抹喜疗妥药膏。两组患者在治疗期间接受相同的护理措施,并于留置针穿刺成功后1~7天评估两组静脉炎的发生率。结果对照组的静脉炎发生率为16.9%,而实验组静脉炎发生率为3.6%,经比较（P〈0.05）,结果有统计学差异性。结论使用喜疗妥药膏预防浅静脉留置针化疗致静脉炎的效果明显优于水胶体透明贴,具有临床推广意义。

Objective To compare the preventive effect of Mucopolysaccharidepolysulfate Cream and Hydrocolloid transparent stickers on phlebitis caused by superficial vein indwelling needle.Methods This study enrolled 121 patients with cervical cancer and been treated with PVB（DDP ＋ Vincristine ＋ Bleomycin）chemotherapy through superficial vein indwelling needle.They were then randomized into control group and experiment group,after successfully indwelling the needle puncture,the control group firstly covered with Hydrocolloid transparent stickers and then used commonsticking transparent film to fixed catheter.The experimental group firstly fixed catheter with 3M post,then avoid the puncture daubedMucopolysaccharidepolysulfate Cream at the proximal end.We accessed the incidence of phlebitisof the two groups one to seven days after indwelling the needle puncture.Results The incidenceof phlebitis of experimental group and the control group was 3.6%and 16.9%respectively,there has significant difference between the two methods（P 〈 0.05）.Conclusions Compare with the Hydrocolloid transparent stickers,the use of Mucopolysaccharidepolysulfate Cream can effectively reduce the occurrence of phlebitis caused by superficial vein indwelling needle.