新疆地区维族与汉族脑梗死急性期患者血尿酸水平对照研究

A Parallel Study of Serum Uric Acid in both Xinjiang Uygur and Han Nationality with Acute Cerebral Infarction

目的:对比观察新疆地区维吾尔族与汉族脑梗死急性期患者的血尿酸(UA)水平。方法:选取脑梗死急性期汉族患者323例(汉族组)与维吾尔族患者144例(维族组),检测血清UA水平,了解TOAST分型与血UA的关系。结果:汉族组和维族组的UA水平分别为(316.17±89.65)、(340.41±87.83)μmol/L,后者高于前者,有显著性差异(t=-2.715,P<0.01)。2组吸烟、饮酒各所占的比例,有显著性差异(P<0.01)。2组TOAST分型各亚型构成比比较,差异无统计学意义(χ2=0.824,P>0.05);2组LAA型血UA水平比较,差异有统计学意义(P<0.05);SAO型、CE型血UA水平比较,差异无统计学意义(P>0.05)。结论:维族与汉族脑梗死急性期患者不同TOAST分型血尿酸水平升高也不同。

Objective： To explore some risk factors between Xinjiang Uygur and Han Nationality patients with acute cerebral infarction based on TOAST classification. Methods： Patients diagnosed with acute cerebral infarction were enrolled, including 144 cases of Uygur Nationality patients and 323 cases of Han Nationality. The serum uric acid（UA） level was detected in all the patients. Results： The serum UA levels were（316.17±89.65） μmol/L in Han patients group and（340.41±87.83） μmol/L in Uygur patients group respectively（P〈0.01）. The percentage of smoking, drinking alcohol and combining coronary heart disease were significantly different between the two groups（P〈0.01）. There was no significant difference in subtype constituent ratios in TOAST classification between the two groups（χ2=0.467, P〈0.05）. For the LAA subtype patients, the levels of blood UV was significantly different between the two groups（P〈0.05）; for the SAO and CE subtype patients, the levels of blood UA showed no significant difference between the two groups（P〈0.05）. Conclusion： In Uygur Nationality and Han Nationality patients with acute cerebral infarction, blood UA level and the various subtypes of TOAST etiology classification show different.