包头地区250例妊娠期妇女部分生化指标的分析

Analysis of partial biochemical index among 250 women during pregnaney in Baotou area

目的探讨包头地区正常妊娠期妇女部分生化指标变化的特征,为临床诊治孕妇相关疾病提供依据。方法采用日立7060型全自动生化分析仪,对250例妊娠孕妇和100例非妊娠妇女采集血液标本,将对象根据情况分为三组妊高征组、正常妊娠组、对照未孕健康组,进行三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、血糖(GLU)生化指标测定,分析结果。结果妊高征组较正常妊娠组TG、TC、LDL-C均显著升高(P<0.05),GLU、HDL-C有所下降,差异有统计学意义(P<0.05),妊高征组较对照未孕健康女性TG、TC、LDL-C、HDL-C均显著升高,而GLU有所下降,差异有统计学意义(P<0.05)。正常妊娠组较对照未孕健康女性TG、TC、LDL-C、HDL-C均显著升高,而GLU有所下降,差异有统计学意义(P<0.05),早期、中期、晚期妊娠各组GLU比对照组略低,差异无统计学意义(P>0.05);中期、晚期妊娠组TC、TG、HDL-C、LDL-C均比对照组高,差异有统计学意义(P<0.05)。结论妊高征孕妇部分生化指标较正常妊娠孕妇有明显改变,应严密监视,采取积极有效的预防和治疗措施。

Objective To investigate the characteristics of biochemical index changes among women during normal pregnancy in Baotou area so as to provide the basis for clinical diagnosis and treatment of pregnant women. Methods Blood samples were collected from 250 pregnant women and 100 non-pregnant women by Hitachi 7060 fully automatic biochemical analyzer.The subjects were divided into three groups of pregnancy hypertension group, normal pregnancy group, and unpregnancy control group.The biochemical indexes of triglyceride（TG）, total cholesterol（TC）, high density lipoprotein（HDL-C）, low density lipoprotein（LDL-C） and blood glucose（GLU） were measured and analyzed. Results The TG, TC and LDL-C were significantly higher in the pregnancy hypertension group than the normal pregnancy group（P〈0.05）,and the GLU and HDL-C decreased with differences of statistical significance（ P〈0.05）.The TG,TC,LDL-C, and HDL-C were significantly higher in the pregnancy hypertension group than the unpregnancy control group,while the GLU decreased with differences of statistical significance（ P〈0.05）.The TG, TC, LDL-C, and HDL-C were significantly higher in the normal pregnancy group than the unpregnancy control group, while the GLU decreased with differences of statistical significance（ P〈0.05）.The GLU in early, middle, and late stages of the pregnancy groups was lower than that in the unpregnancy control group with differences of no statistical significance（ P〉0.05）.The TC, TG,HDL-C, and LDL-C in early, middle, and late stages of the pregnancy groups were higher than those in the unpregnancy control group with differences of statistical significance（P〈0.05）.Conclusion The biochemical indexes of the pregnant women with pregnancy hypertension have significant changes compared with the normal pregnant women,who deserve close surveillance,and active and effective prevention and treatment measures.