保妇康栓联合鸦胆子仁浸剂治疗高危HPV感染的CIN Ⅰ的疗效

The clinical observation of Brucea javanica joint bolt Baofukang treatment of CIN I caused by the infection of high-risk HPV

目的探讨保妇康栓联合鸦胆子仁浸剂治疗高危HPV感染的CINⅠ的临床疗效。方法我院妇科门诊就诊女性诊断CINⅠ同时合并高危HPV感染60例,将患者随机分为3组:联合治疗组(n=28)、对照组(n=22),分别应用保妇康栓联合鸦胆子仁浸剂、单纯保妇康栓治疗,空白对照组(n=10)不使用任何药物,比较疗程结束后HPV转阴、宫颈CINⅠ的变化情况。结果联合治疗组和对照组HPV转阴率分别为58.2%和55.3%,高于空白对照组(P<0.05);对CINⅠ治疗有效率分别为61%和40.9%,高于对照组20%(P<0.05)。结论保妇康栓联合鸦胆子仁浸剂治疗合并HPV感染的CINⅠ安全、有效。

Objective To discuss clinical curative effect of Brucea javanica joint bolt Baofukang treatment of CIN Ⅰ caused by the infection of high-risk HPV.Methods A total of 60 women diagnosed as CIN Ⅰ combined with high-risk HPV infection were randomly divided into 3 groups：Combination group（n=28）,The control group（n=22）.Application of combined brucea ren bao fu Kang Shuan infusions,Simple woman Kang Shuan treatment.Blank control group（n=10）Do not use any drugs.The response rales of CIN Ⅰ and high-risk HPV infection were compared.Results Combined treatment group and The control group HPV turn rate respectively 58.2% vs 55.3%,Higher than the blank control group（P〈0.05）.For CIN Ⅰ treatment efficiency respectively 61% vs 40.9%,20% higher than the control group（P〈0.05）.Conclusion Baofukang suppository combined with Brucea javanica in the treatment of CINⅠand high-risk HPV infection is a safe and effective method.