调强放疗联合顺铂对宫颈癌疾病的治疗效果评述

Efficacy of Radiotherapy Combined With Cisplatin in the Treatment of Cervical Cancer

目的研究调强放疗联合顺铂对宫颈癌疾病的治疗效果。方法病例来源：我院2010年4月~2012年2月住院接受治疗的83例宫颈癌疾病患者。患者分组方法 ：随机抽签法。83例患者分为调强放疗组和调强放疗＋化疗组两个组别。调强放疗组给予单纯调强放疗;调强放疗＋化疗组给予调强放疗联合顺铂治疗。观察指标：（1）近期缓解率、1年生存率、3年生存率;（2）副作用率。结果 （1）调强放疗＋化疗组相比于调强放疗组近期缓解率、1年生存率相似,经χ^2检验,差异有统计学意义,P〈0.05;3年生存率更高,经χ^2检验,差异有统计学意义,P〈0.05;（2）调强放疗＋化疗组相比于调强放疗组副作用率更低,经χ^2检验,差异有统计学意义,P〈0.05。结论调强放疗联合顺铂对宫颈癌疾病的治疗效果确切,可提升患者远期生存率,减轻毒副作用。

Objective Intensity modulated radiation therapy the joint effect of cisplatin in the treatment of cervical disease. Methods The cases of sources： from April 2010 to February 2012 in the hospital for treatment of 83 cases of patients with cervical cancer disease. Patients grouping methods： random draw method. 83 patients were divided into intensity modulated radiation therapy and intensity modulated radiotherapy＋chemotherapy groups. Intensity modulated radiation therapy intensity-modulated radiation therapy group was given simple. Intensity modulated radiation therapyintensity modulated radiotherapy＋chemotherapy group was given with cisplatin therapy. Observation indexes：（1） The recent response rate, 1 year survival rate, 3 year survival rate.（2） Deputy action rate. Results（1） Intensity modulated radiotherapy＋chemotherapy group compared with intensity modulated radiotherapy group recently remission rate, 1 year survival rates are similar, χ~2 statistics treatment have significant difference, P〈0.05. The 3 year survival rate is higher, the χ~2 statistics processing has a significant difference, P〈0.05. Intensity modulated radiation therapy.（2） The side effect rate was lower in the intensity modulated radiotherapy＋chemotherapy group compared with the intensity modulated radiation therapy group, χ~2 statistics treatment have significant difference, P〈0.05. Conclusion Intensity-modulated radiation therapy of combined cisplatin in the treatment of cervical disease effect is exact, can improve patients＇ long-term survival rate, reduce side effects.