郁证理论与癌病发生关系研究

Study on the Relationship between Stagnation Syndrome Theory and Cancer Occurrence

中医学郁证理论起源于《黄帝内经》中提出的"五郁"和"情志致郁"理论。东汉医家张仲景将"郁"视为疾病发生的关键因素,初步形成了较完整的郁证辨证论治体系。后世医家阐幽发微,完善了郁证理论的内涵,尤以朱丹溪的"六郁"理论为代表。郁证理论的要旨在于:人体气血津液郁滞不通、迟留不畅则发病。其中气郁为诸郁之首,在郁证的病机演变中起关键作用,气郁日久则致食积、痰饮、瘀血等有形病理产物,临床可表现为癥瘕积聚、瘰疬瘿瘤。有形病理产物不能速去,郁积日久则为癌前疾病,进而发生癌前病变,若不加干预则发为癌病。故郁证理论在癌病发生过程中意义重大,应加以深入挖掘,进一步探究郁证理论在癌前疾病、癌前病变中的应用,进而为癌病辨治提供参考。

The stagnation syndrome theory originates from the theory of ＂five- stagnation＂ and ＂stagnation caused by emotional disorders＂ in The Yellow Emperor＇s Inner Classic. ZHANG Zhongjing,a physician in the East Han Dynasty,regarded ＂stagnation＂ as the key factor in the occurrence of disease,a relatively complete syndrome differentiation and treatment system for stagnation syndrome being formed. Physicians of later generations developed this theory,especially ＂six- stagnation＂ theory by ZHU Danxi. The essence of stagnation syndrome theory is as follows：the stagnation of qi,blood and body fluids cause disease,and qi stagnation is the chief cause. It plays a key role in disease mechanism,and long term stagnation of qi leading to accumulation and stagnation of food,phlegm and blood stasis,manifesting as abdominal masses,scrofula,goiter and tumor. These visible pathological products can＇t be removed at once,resulting into precancerous disease and precancerosis,and even cancer without timely intervention and treatment. So stagnation syndrome theory is significant in cancer occurrence,and therefore it should be further studied to find out its application in precancerous disease as well as precancerosis,and to provide a reference for clinical treatment.