摘要
目的探究结直肠癌(CRC)中肝癌衍生生长因子和p53蛋白的表达相关性。方法应用免疫组化染色法检测80例CRC和10例正常结直肠黏膜组织者中的肝癌衍生生长因子(HDGF)的表达,取30例CRC组织检测p53蛋白的表达水平。结果 80例CRC中HDGF阳性率为66.7%,而正常人群的结直肠黏膜组织均为阴性;30例CRC组织中p53蛋白的阳性率为70.0%,而正常结直肠黏膜者呈阴性。结论 HDGF和P53蛋白在结直肠癌组织中的表达高于正常结直肠癌组织。
Objective Exploration of colorectal cancer（CRC） in hepatoma-derived growth factor and p53 protein expression correlation. Methods CRC 80 cases and 10 cases of normal colorectal mucosa organizer of hepatoma-derived growth factor（HDGF） expression by immunohistochemical staining,30 cases taken to detect the expression levels of p53 protein in CRC tissue. Results 80 cases of CRC in HDGF positive rate 66.7%,while the colorectal mucosa normal population was negative. The positive rate of 30 cases of CRC of p53 protein was 70.0%,while the normal colorectal mucosa were negative. Conclusion The expression of HDGF and P53 protein in colorectal cancer tissues was significantly higher than that in normal colorectal cancer tissues.
出处
《中国卫生标准管理》
2016年第4期171-172,共2页
China Health Standard Management
