发热病人病因判断中血细胞形态学检验的应用研究

Study on the Application of Blood Cell Morphological Examination in the Etiology of Fever Patients

目的探讨血细胞形态学检验在发热病人病因判断中的应用价值。方法随机抽取广东省汕头市龙湖人民医院2014年1月到2014年12月间收治的发热患者200例作为研究对象,并以200例健康受检者作为对照,分别对两组受检者的血液标本实施常规检验及血涂片染色显微镜检,在显微镜下观察各种细胞的细胞形态学变化,计算形态异常检出率,并分别比较其Hct、RDWSD、MCH、MCHC、MCV的检测水平。结果观察组外周血细胞异常变化检出率为60.0%,对照组仅为7.5%,其中,白细胞变化、大细胞性贫血、小细胞性贫血、异性淋巴细胞变化、异常细胞等的检出率均显著高于对照组,比较有统计学差异(P<0.05)。而Hct、RDW-SD、MCHC、MCV等指标的检测结果也均显著高于对照组,比较有统计学差异(P<0.05)。结论通过对血液标本的血细胞形态进行观察,能够对发热疾病的发生发展进行判断,一定程度上明确患病的原因,并为其临床治疗提供指导依据。

Objective To investigate the application value of the morphological examination of bloodcells in the pathogenesis of fever patients. Methods 200 cases of fever patients treated in our hospitalfrom January 2014 to December 2014 were randomly selected as the research object, and 200 healthysubjects were used as control, and the blood samples of the two groups were examined by routine test andblood smear staining. The morphological changes of the cells were observed under microscope, and thedetection rate of RDW - SD,MCH,MCHC,MCV and Hct were compared. Results The detection rateof abnormal changes in peripheral blood cells of the observation group was 60% , and the control group was 1. 5%, which was significantly higher than that of the control group （P 〈0. 05） . The Hct, RDW -SD, MCHC, MCV and other indicators of the test results were significantly higher than the control group,the difference was statistically significant （ P 〈 0. 05 ） . Conclusion Through observing the blood cellmorphology of blood samples, it can judge the occurrence and development of fever, and to some extent,it can provide guidance for clinical treatment.