急性呼吸窘迫综合征研究进展

Advances of acute respiratory distress syndrome

急性呼吸窘迫综合征(ARDS)是由炎症刺激损伤导致肺泡屏障破坏,液体渗出,导致低氧血症。ARDS的死亡率极高。虽然ARDS的治疗取得较大进展,但行之有效的方法十分有限,故早期识别危险因素及避免恶化因素十分重要。本文就ARDS定义、病理生理学发病机制及目前治疗手段进行综述。

The acute respiratory distress syndrome（ ARDS） is a form of severe hypoxemic respiratory failure that is characterized by inflammatory injury to the alveolar capillary barrier,with extravasation of protein-rich edema fluid into the airspace. Although many techniques to treat ARDS have been investigated over the past several decades,the efficient therapies were limited. Therefore,early recognition of ARDS risk factors and to avoid aggravation is important. This paper reviewed recent studies about ARDS definition and the pathogenesis of pathophysiology as following.