期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

儿童急性淋巴细胞白血病基因拷贝数变异研究及应用进展：第57届美国血液学会年会报道 被引量：1

Advances in research and application of copy number variants in pediatric acute lymphoblastic leukemia： reports from the S7th American Society of Hematology annual meeting
原文传递
导出
摘要 近年来的研究表明，一些基因的拷贝数变异（CNV）与儿童急性淋巴细胞白血病（ALL）的进展及预后密切相关。文章结合2015年第57届美国血液学会（ASH）年会上的报道就相关研究进展进行介绍。 Recent studies showed that copy number variations in certain genes are closely correlated to progression and prognosis of pediatric acute lymphoblastic leukemia. Relevant reports in the 57th American Society of Hematology（ASH） annual meeting in 2015 will be reviewed together with research progress in recent years.
作者 陈雪 窦丹丹 张阳 王彤 刘红星
机构地区 河北燕达陆道培医院病理和检验医学科
出处 《白血病．淋巴瘤》 CAS 2016年第3期139-143,共5页 Journal of Leukemia & Lymphoma
关键词 白血病 淋巴细胞 急性 拷贝数变异 危险分层 治疗选择 美国血液学会年会 Leukemia, lymphoblastic, acute Copy number variations Risk stratification Treatment options American Society of Hematology annual meeting
分类号 R733.71 [医药卫生—肿瘤]
  • 相关文献

参考文献37

  • 1Hunger SP,Mullighan CG. Acute lymphoblastic leukemia in children[J]. N Engl J Med, 2015, 373 ( 16): 1541-1552. DOI:10.1056/NEJMral400972.
  • 2Hunger SP, Mullighan CG. Redefining ALL classification : towarddetecting high-risk ALL and implementing precision medicine [ J ].Blood, 2015,125(26) : 3977-3987. DOI: 10.1182/blood-2015-02-580043.
  • 3Lim JY, Bhatia S,Robison LL,et al. Genomics of racial and ethnicdisparities in childhood acute lymphoblastic leukemia [ J ]. Cancer,2014,120(7) : 955-962. D01:10.1002/cncr.28531.
  • 4Kuiper RP, Schoenmakers EF, van Reijmersdal SV, et al. High-resolution genomic profiling of childhood ALL reveals novel recurrentgenetic lesions affecting pathways involved in lymphocytedifferentiation and cell cycle progression [ J ]. Leukemia, 2007, 21(6):1258-1266. DOI: 10.1038/SJ.LEU.2404691.
  • 5Woo JS, Alberti MO, Tirado CA. Childhood B-acute lymphoblasticleukemia: a genetic update [ J ] . Exp Hematol Oncol, 2014, 3 : 16.DOI: 10.1186/2162-3619-3-16.
  • 6Mullighan CG, Phillips LA, Su X, et al. Genomic analysis of theclonal origins of relapsed acute lymphoblastic leukemia [ J ]. Science,2008,322 (5906 ) : 1377-1380. DOI : 10.1126/science. 1164266.
  • 7Schwab CJ, Chilton L, Morrison H, et al. Genes commonly deleted inchildhood B-cell precursor acute lymphoblastic leukemia : associationwith cytogenetics and clinical features [ J ] . Haematologica, 2013,98(7):1081-1088. D01:10.3324/haematol.2013.085175.
  • 8Mullighan CG, Goorha S,Radtke I,et al. Genome-wide analysis ofgenetic alterations in acute lymphoblastic leukaemia [ J ]. Nature,2007,446(7137 ) : 758-764. DOI: 10.1038/NATURE05690.
  • 9Tomoyasu C, Imamura T, Yano M,et ai. Analysis of copy numberabnormalities of 86 acute lymphoblastic leukemia cell lines based onthe genetic subtypes [ J ]. Blood, 2015, 126(23): Abstract 1424.
  • 10Pechanska P, Kunz J, Rausch T, et al. Gene panel sequencing ofprimary and relapsed pediatric T-ALL shows that relapse-specificmutations are diverse and mostly non-recurrent [ J ]. Blood, 2015,126 (23 ) : Abstract 1428.

引证文献1

二级引证文献1

白血病．淋巴瘤
2016年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部