遗传性聋的患病情况和遗传构成

Study on the Population Genetics of Hereditary Deafness

作者在对226例无明显致聋原因感觉神经性聋进行分离分析的基础上,根据Hardy-Wein-berg定律,计算出遗传性感觉神经性聋(HSNHL)不同遗传方式的基因频率和杂合子频率,并对其群体患病率进行探讨。

From segregation analysis of 220 cases of sensorineural heaing loss, the gene and heteroz-ygote freguency of each hereditary mode was calculated by Hardy-Weinberg law respectively.The morbidity of hereditary deafness was 3.3‰.