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结肠癌腹腔内淋巴化疗的临床分析

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摘要 目的探讨卡铂联合善宁对结肠癌患者实施预防性腹腔内淋巴转移化疗的临床效果。方法随机选取我院2010年9月—2014年12月期间收治的结肠癌术后腹腔淋巴结阳性患者90例,均分成2组,观察组患者在术后使用卡铂200 mg+善宁0.2 mg进行腹腔内淋巴化疗,对照组患者仅采用卡铂200 mg进行腹腔内化疗。对2组患者化疗后淋巴结周围的铂浓度、腹膜后淋巴结转移情况进行观察记录。结果观察组患者的中央淋巴结、中间淋巴结、边缘淋巴结的铂浓度明显高于对照组;淋巴结转移率低于对照组,差异均具有显著性(P<0.05)。结论采用善宁联合卡铂进行腹腔内淋巴化疗是一种有效的结肠癌化疗方法,有助于降低癌肿复发率,建议在临床上进一步推广。
作者 吕运海
出处 《基层医学论坛》 2016年第7期927-928,共2页 The Medical Forum
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