摘要
氢气在自然界中广泛分布,无色无味,非金属且极度易燃。目前研究证实氢气对脓毒症、代谢综合征、脑缺血再灌注损伤、肺损伤、肠道损伤、糖尿病等多种疾病有预防和治疗作用。而氢气治疗疾病的主要机制包括抗氧化、抗炎和抗凋亡,另外还发现氢气可以影响FcεRI介导的信号转导,核因子kB信号调节通路等。本文对目前氢气治疗疾病的研究进展作一综述。
Widely distributed in nature, hydrogen is colorless, odorless, nonmetal and extremely flammable. Recent studies have confirmed that hydrogen has preventive and therapeutic effect on sepsis, metabolic syndrome, cerebral ischemia reperfusion injury, lung injury, intestinal injury, diabetes and other diseases. The main mechanisms of hydrogen treatment of diseases consists of anti-oxidation, antiinflammatory and anti-apoptosis. And it is observed that hydrogen can affect the signal transduction of FcεRI mediates and the NF-kB signal regulating circuit, etc. In this paper, we will review the recent progresses of hydrogen in diseases.
出处
《国际呼吸杂志》
2016年第5期397-400,共4页
International Journal of Respiration
关键词
氢气
临床应用
Hydrogen
Clinical application