桃核承气汤治疗急性胰腺炎并发腹腔高压临床观察

Clinical observation of Taohe Chengqi Decoction on patients with acute pancreatitis complicated with intra-abdominal hypertension

目的:观察桃核承气汤辅助治疗急性胰腺炎并发腹腔高压的临床疗效。方法:选择急性胰腺炎并发腹腔高压患者63例,随机分为2组,对照组(31例)和治疗组(32例),对照组采用单纯西医综合治疗,治疗组在此基础上口服桃核承气汤,观察临床疗效。结果:治疗组患者腹痛、腹胀症状改善明显,白细胞计数、血淀粉酶、血脂肪酶和肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)含量显著下降,腹内压亦明显降低,与对照组比较,差异有统计学意义(P<0.05)。结论:桃核承气汤辅助治疗急性胰腺炎并发腹腔高压有良好的临床疗效。

Objective： To observe the clinical efficacy of Taohe Chengqi Decoction in patients with acute pancreatitis（AP） complicated with intra-abdominal hypertension（IAH）. Methods： Sixty-three patients with AP complicated with IAH were randomly divided into a control group（31 cases） and a treatment group（32 cases）. The control group was given the comprehensive treatment of western medicine. The treatment group was treated with Taohe Chengqi Decoction by oral administration based on the treatment of western medicine. The clinical effects were observed. Results： In the treatment group, the abdominal pain and abdominal distension were obviously improved; The white blood cell count, the contents of blood amylase, lipase, TNF-α and CRP were significantly decreased; The intra-abdominal pressure significantly decreased. All the indexes had significant statistical differences when compared with these in control group（P〈0.05）. Conclusion： Taohe Chengqi Decoction has a good clinical effect as adjuvant therapy in patients with AP complicated with IAH.