血常规检查中胆红素对参数的影响

The effect of bilirubin on parameters of blood routine examination

目的探讨血常规检查中胆红素对参数的影响情况。方法选择我院生化检测中40例胆红素异常患者,与同期40例健康者对照研究。检测研究者的血常规,分析白细胞计数、血红蛋白以及血小板等的变化,此外检测观察组0.5、1、2、4h的血常规,进一步分析血常规检查中胆红素对参数的影响。结果观察组白细胞计数、血红蛋白均显著高于对照组,血小板计数低于对照组,两组比较差异有统计学意义(P<0.05);两组患者的血小板体积分布宽度、血细胞比容、平均血小板体积、平均血红蛋白浓度、血小板压积、红细胞体积分布宽度比较差异无统计学意义(P>0.05);观察组血常规检查中胆红素作用时间对参数无影响(P>0.05)。结论胆红素增高会导致白细胞计数、血红蛋白出现假性升高,血小板计数出现假性下降,血常规检查中胆红素作用时间对参数无影响。

Objective To study the effect condition of bilirubin on parameters of blood routine examination. Methods To select 40 patients with abnormal bilirubin who were carried out biochemical detection in our hospital as observation group, and to select another 40 healthy subjects as control group. To detect the blood routine examination of the research objects, to analyze the changes of leukocyte count, hemoglobin, and blood platelets and etc., furthermore, to detect the blood routine examination at 0.5, 1, 2, 4h in observation group, to further analyze the effect of bilirubin on parameters of blood routine examination. Results The differences of the distribution width of platelet volume, hematocrit, average platelet volume, average hemoglobin concentration, platelet volume, distribution width of corpuscular volume was no statistical significance compared with the two groups（P 〉0.05）, the action time of bilirubin in observation group has no effect with the parameters of blood routine examination（P 〉0.05）. Conclusion The increased bilirubin could cause the occurrence of false increase on leukocyte count, hemoglobin, and false decrease on platelet count. The action time of bilirubin has no effect with the parameters of blood routine examination.