ALA光动力疗法治疗面部痤疮临床疗效研究

Clinical effect of ALA photodynamic therapy on facial acne

目的探讨5-氨基酮戊酸(ALA)光动力疗法治疗面部痤疮的临床疗效。方法采用随机单盲临床试验将90例面部痤疮患者分成两组,各45例,观察组采取ALA光动力治疗,对照组采取常规药物治疗,比较两组的临床疗效。结果观察组治疗4周、8周后总有效率均明显好于对照组,观察组治疗后皮肤油脂明显少于对照组,两组均无明显不良反应。结论 ALA光动力疗法治疗面部痤疮的疗效显著,值得应用。

Objective To investigate the clinical effect of 5-（ALA） in the treatment of facial acne vulgaris. Methods 90 patients with facial acne were divided into 2 groups, 45 cases in each group. Observation group was treated with ALA photodynamic therapy, control group was treated with routine drugs. The clinical efficacy of the 2 groups were compared. Results Total effective rate of observation group was significantly better than that the control group at 4 weeks and 8 weeks after treatment. Skin grease of the observation group was significantly less than the control group. 2 groups had no obvious adverse reactions. Conclusion ALA photodynamic therapy has significant efficacy in the treatment of facial acne, which is worthy of application.