间断蓝光照射联合枯草杆菌二联活菌颗粒及茵栀黄口服液治疗新生儿黄疸临床疗效分析

Clinical Effect of Intermittent Blue Light Irradiation Combined with Medilac-Vita and Yinzhihuang in Neonatal Jaundice

目的:探讨间断蓝光照射联合枯草杆菌二联活菌颗粒(妈咪爱)及茵栀黄口服液治疗新生儿黄疸的临床疗效。方法:选取我院2012年2月到2014年12月收治的69例采用间断蓝光照射联合枯草杆菌二联活菌颗粒及茵栀黄口服液治疗的新生儿黄疸患儿的临床资料,将其设为研究组,选取同期只采用间断蓝光照射治疗的62例患儿资料,将其设置为对照组,比较两组患儿的临床治疗效果及其治疗前后血清胆红素水平变化。结果:研究组总有效率为89.9%,对照组总有效率为72.6%,两组比较差异有统计学意义(P<0.05);治疗3 d后研究组血清胆红素水平下降明显优于对照组,两组比较差异有统计学意义(P<0.05);研究组不良反应发生率为2.9%,对照组为4.4%,两组比较差异无统计学意义(P>0.05)。结论:间断蓝光照射联合枯草杆菌二联活菌颗粒、茵栀黄口服液治疗新生儿黄疸效果显著,可有效降低患儿的血清胆红素浓度,值得临床推广。

Objective： To investigate the clinical effect of intermittent blue light irradiation combined with Medilac-Vita and Yinzhihuang oral liquid in the treatment of neonatal jaundice. Methods： In our hospital from February 2012 to December 2014,69 children as the study group were treated with intermittent blue light irradiation combined with Medilack-Vita and Yinzhihuang oral liquid.Sixty two children as the control group were treated with intermittent blue light irradiation. The serum bilirubin levels before and after treatment and the effect of the two groups were compared. Results： The total effect of the study group（ 89.9%） was better than that of the control group（ 72.6%）（ P〈0.05）. After treatment in 3 days,the serum bilirubin level of study group was lower than that of control group,there was statistical significance between the two groups（ P〈0.05）. The incidence rate of adverse reactions was 2.9% in study group,the incidence rate of adverse reactions of the control group was 4.4%,there was no statistical significance between the two groups（ P〈0.05）. Conclusion： Intermittent blue light irradiation combined with Medilac-Vita and Yinzhihuang oral liquid in treating neonatal jaundice,can decrease serum bilirubin concentration significantly,it is worthy of promotion.