运动对内质网应激与胰岛素抵抗之间的影响被引量：2

Influence of Exercise Between the Endoplasmic Reticulum Stress and Insulin Resistance

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摘要二型糖尿病一直都是威胁人类健康的疾病之一,它的主要特征是胰岛β细胞胰岛素分泌不足和胰岛素抵抗。而内质网应激与胰岛素抵抗之间的联系是最近研究的热点。而大多数研究也表明运动能够缓解二型糖尿病的症状,改善细胞胰岛素抵抗。并且患者经过一系列的耐力运动之后,糖耐量有显著的提高,血糖水平也趋于稳定。众多研究表明,运动可以提高胰岛素受体的敏感性,并且运动与内质网应激也存在一定的关系。本文主要综述近些年来,内质网应激和胰岛素抵抗之间的关系,以及运动在其中扮演着何种角色,从而为相关研究者提供参考借鉴。 Type 2 diabetes has been one of the disease threat to human health whose main characteristic is islet beta cells insulin hypo secretion and insulin resistance.The connection between the endoplasmic reticulum stress and insulin resistance is a hotspot of recent research.Furthermore,most of the research has shown that exercise can relieve the symptoms of type 2 diabetes,improving the condition of cells insulin resistance.After a series of endurance sports,patients have significant improvement of glucose tolerance and stabilization of blood sugar levels.Numerous studies have shown that exercise can improve the sensitivity of insulin receptor and exercise also has certain relations with endoplasmic reticulum stress.This article mainly reviews the relationship between the endoplasmic reticulum stress and insulin resistance and the role the exercise play in it in the most recent years,providing a reference for related researchers.

作者戈哲

机构地区华东师范大学体育与健康学院

出处《四川体育科学》 2016年第2期29-34,共6页 Sichuan Sports Science

关键词运动内质网应激 UPR 胰岛素抵抗 Exercise Endoplasmic reticulum stress UPR Insulin resistance

分类号 G804.22 [文化科学—运动人体科学]

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