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血浆皮质醇水平对STEMI患者急诊PCI术后早期心血管事件的预测价值 被引量:4

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摘要 目的分析血浆皮质醇(COR)水平对ST段抬高性急性心肌梗死(STEMI)患者急诊PCI术后早期心血管事件的的预测价值。方法 79例STEMI患者,发病6 h内行急诊PCI术。根据患者1个月内是否发生主要恶性心脏事件分为事件组和无事件组,记录两组患者年龄、性别、BMI、吸烟史、既往病史及治疗经过,比较两组COR水平、左室射血分数(LVEF)、Gensini积分。采用受试者工作特征曲线计算COR水平预测急诊PCI术后STEMI患者发生早期心血管事件的诊断临界值。采用Cox比例风险回归模型分析STEMI患者发生早期心血管事件的危险因素。结果事件组16例,无事件组63例。事件组、无事件组COR水平分别为29.1、19.1μg/d L,两组比较,P〈0.05。COR水平取截断值为20.5μg/d L时,预测急诊PCI术后STEMI患者发生早期心血管事件的灵敏度为66.5%、特异度为69.3%。COR水平(HR=2.20,95%CI:1.19-6.53,P=0.02)是STEMI患者急诊PCI术后发生早期心血管事件的独立预测因子。结论血浆COR水平是STEMI患者急诊PCI术后发生早期心血管事件的独立预测因子。
出处 《山东医药》 CAS 北大核心 2016年第11期49-51,共3页 Shandong Medical Journal
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