胃肠安丸治疗功能性腹泻60例临床观察

Clinical observation of 60 cases of functional diarrhea treated with gastrointestinal safety pill

目的:评价胃肠安丸治疗功能性腹泻的疗效和安全性。方法:将120例患者随机分为2组:治疗组60例给予胃肠安丸治疗,对照组60例舒丽启能(马来酸曲美布汀片)治疗,疗程为4周。比较治疗组不同观察时点各症状积分情况,并比较治疗组与对照组临床疗效,同时观察有无副作用。结果:治疗组有效率98.3%,对照组有效率61.67%,2组比较差异有统计学意义(P<0.05);治疗14d有效率70.00%,治疗28d有效率98.3%,2组比较差异有统计学意义(P<0.05);治疗组不同时点各症状积分与治疗前比较,差异有统计学意义(P<0.05);用药期间未发现明显不良反应。结论:胃肠安丸治疗功能性腹泻效果显著,且随着疗程的延长有效率逐渐提高,疗程长,效果好,是安全、有效的药物。

Objective： To evaluate the efficacy and safety of the treatment of functional diarrhea by the gastroin- testinal safety of the pill. Methods： 120 patients were randomly divided into 2 groups, treatment group 60 cases were given Weichang＇ an pill treatment, 60 cases in control group were given to Shu Liqi （trimebutine maleate tablets） treat- ment, treatment for 4 weeks. Comparison of different treatment groups at different time points in each symptom score, and compare the clinical efficacy of the treatment group and the control group, while observing the side effect. Results： The total effective rate was 98.3% in treatment group and 61.67% in control group, the difference was statistically significant （P〈0.05）, the treatment efficiency was 70% in 14 days, 28 days in 2 days, the difference was statistically significant （P〈O.05）. The difference was statistically significant （P〈0.05）. Conclusion： The effect of the treatment of the gastrointestinal safety of the treatment of functional diarrhea is remarkable, and with the extension of the course of treatment, the efficiency is gradually increased, the treatment process is long, the effect is good, it is safe and effective.