Genex可注射型人工骨在胫骨平台粉碎性骨折治疗中的应用

Genex injectable bone graft in the treatment of comminuted fracture of tibial plateau

目的探讨吉莱骨粉（Genex）可注射型人工骨在胫骨平台粉碎性骨折治疗中的临床效果。方法将本院收治的胫骨平台粉碎性骨折60例，需要手术治疗且有明显的骨缺损需植骨修复重建的患者按照数字表法随机分为两组，对照组30例采用传统的自体骨植骨治疗；观察组30例给予自体骨／Genex可注射型人工骨填充修复（可注射型硫酸钙一磷酸钙制剂复合填充）治疗，并比较两组的临床效果。结果观察组的总优良率为93．33％明显高于对照组的76．67％（P〈0．05），对照组的骨折愈合时间为（18．72±4．58）周；观察组的骨折愈合时间为（14．63±5．98）周，两组比较差异具统计学意义（t=6．5864，P=0．0382）。结论Genex可注射型人工骨在胫骨平台粉碎性骨折能够缩短患者的治疗时间，使伤肢的功能得到更好的恢复。

Objective To explore the clinical effect of Gillet bone meal （Genex） injectable bone graft in the treatment of comminuted fracture of tibial plateau. Methods 60 cases of comminuted fracture of tibial plateau in our hospital who need operation treatment and bone graft reconstruction because of obvious bone defect were divided into two groups in accordance with the random number table. 30 cases in control group were treated by traditional autogenous bone graft, while 30 cases in observation group were treated by autologous bone/Genex injectable bone graft filling repair （injectable calcium sulfate, calcium phosphate preparation composite filling）. Compared the clinical effect of two groups. Results The excellent and good rate was 93.33% in observation group, obviously higher than 76.67% in control group （P〈0.05）; fracture healing time in observation group was （14.63＋5.98） weeks, that in control group was （18.72A=4.58） weeks, with statistically significant difference between two groups （t=6.5864, P=0.0382）. Conclusion Genex injectable bone graft in the treatment of comminuted fracture of tibial plateau can shorten treatment time of patients, make the function of injured limbs recover better.