颅内血肿微创清除术联合亚低温治疗高血压脑出血患者的疗效观察

Clinical efficacy of minimally invasive surgery for intracranial hematoma combined with mild hypothermia in the treatment of patients with hypertensive intracerebral hemoirrhage

目的探讨颅内血肿微创清除术联合亚低温在高血压脑出血患者治疗中的临床效果。方法选取本院2014年10月至2015年10月诊治的60例高血压脑出血患者，采用随机对照方法将患者分为对照组和实验组，对照组采用颅内血肿微创清除术治疗，实验组在对照组基础上术后联合亚低温治疗，比较两组患者临床疗效。结果两组患者治疗前ESS、BI评分比较差异无统计学意义（P〉0．05），实验组治疗后ESS、BI评分显著高于对照组（P〈0，05），两组患者重残、植物生存率比较差异无统计学意义（P〉0．05），实验组恢复良好、中残率显著高于对照组（P〈0．05），实验组病死率显著低于对照组（P〈0．05），两组患者治疗前NIHSS评分比较差异无统计学意义（P〉0．05），实验组治疗1个月后、3个月后NHISS评分显著低于对照组（P〈0．05）。结论高血压脑出血患者在颅内血肿微创清除术治疗基础上联合亚低温治疗效果理想，值得推广应用。

Objective To investigate clinical efficacy of minimally invasive surgery for intracranial hematoma combined with mild hypothermia in the treatment of patients with hypertensive intracerebral hemoirrhage （HICH）. Methods 60 cases of HICH in our hospital from October 2014 to October 2015 were divided into control group and experimental group with randomized controlled method, Control group received minimally invasive surgery for intracranial hematoma, and experimental group received mild hypothermia on the basis of control group. Compared clinical efficacy of two groups. Results There were no statistically significant differences in ESS score and BI score between two groups before treatment （P〉0.05）; ESS score and BI score in experimental group after treatment were significantly higher than those in control group （P〈0.05）. There were no statistically significant differences in the rates of severe disability, plant survival between two groups （P〉0.05）, the rates of good recovery, moderate disability in experimental group were higher than those in control group （P〈0.05）, the mortality in experimental group was lower than that in control group （P〈0.05）. There was no statistically significant difference in NIHSS score between two groups before treatment （P〉0.05）; NIHSS score in experimental group after 1, 3 months ＆treatment were significantly lower than those in control group （P〈0.05）. Conclusion Minimally invasive surgery for intracranial hematoma combined with mild hypothermia in the treatment of patients with HICH has ideal therapeutic effect, worthy of clinical application.