微创颅内血肿清除术治疗早期高血压脑出血的临床疗效

Clinical effect of early application of minimally invasive evacuation of hematoma in the treatment of hypertensive intra cerebral hemorrhage

目的探讨微创血肿穿刺术治疗早期高血压脑出血的临床疗效。方法将2014年1～12月我院收治的87例高血压脑出血患者随机分成观察组（44例）和对照组（43例）,观察组采用早期微创血肿清除术治疗,而对照组采用小骨窗血肿清除术治疗。比较两组患者治疗后的临床疗效、血清炎症因子水平及神经功能缺损程度。结果观察组患者治愈率与总有效率显著高于对照组（P〈0.05）;观察组术后的IL-6、TNF-α水平均显著低于对照组（P〈0.05）。观察组术后7 d与术后14 d的GCS评分均显著高于对照组（P〈0.05）。结论早期应用微创颅内血肿清除术能减轻高血压、脑出血急性期炎症因子水平和神经功能缺损。

Objective To explore the clinical effect of minimally invasive hematoma aspiration in the treatment of early hypertensive intra cerebral hemorrhage（HICH）. Methods A total of 87 patients with HICH were randomly divided into observation group（44 cases） and control group（43 cases）. The observation group was treated with minimally invasive removal of intracranial hematomas, while the control group was treated with key hole evacuation of hematoma approach.The curative effect, inflammatory factors levels and glasgow coma scale score（GCS） were compared. Results The cure rate and total effective rate in observation group were significantly higher than those in control group（P〈0.05）. The levels of IL-6 and TNF-α in observation group after treatment were significantly lower than those in control group（P〈0.05）. The GCS score of observation group 7 d and 14 d after treatment were significantly higher than that in control group（P〈0.05）. Conclusion Treatment of minimally invasive evacuation of hematoma surgery for HICH can reduce level of inflammatory factors neurologic impairment in acute stage of cerebral hemorrhage.