支气管镜介入冷冻治疗支气管结核临床研究

Clinical study of frozen bronchoscopic intervention in treatment of bronchial tuberculosis

目的研究支气管镜介入冷冻治疗支气管结核的临床疗效。方法选取我院2013年8月～2014年8月收治的支气管结核患者92例,随机分为研究组与对照组,每组46例。对照组采用常规治疗,研究组采用支气管镜介入冷冻治疗。观察两组的冷冻效果、临床疗效和不良反应等。结果研究组患者经过一段时间的治疗后,总有效率为97.8%,对照组的总有效率为87.0%,两组对比差异具有统计学意义（P〈0.05）。经过半年的治疗后,对照组的痰菌转阴率为69.6%,研究组的痰菌转阴率为89.1%,两组对比,差异具有统计学意义（P〈0.05）。治疗过程中均无严重不良反应。结论对于支气管结核病来说,采用支气管镜介入冷冻治疗的方法疗效更佳,能够有效地改善临床症状,且较为安全,值得在临床中推广。

Objective To investigate the clinical efficacy of bronchoscopic interventional freezing in treatment of bronchial tuberculosis. Methods A total of 92 cases of patients with bronchial tuberculosis were treated in our hospital from August 2013 to August 2014 were selected, were randomly divided into study group and control group of 46 people. Patients in the control group were treated with routine treatment, and the study group was treated with the interventional therapy of bronchial lens and the effect of freezing, clinical curative effect and adverse reaction of two groups were observed. Results After a period of treatment, the total effective rate of study group was 97.8%, the control group was 87.0%, the difference was statistically significant（P〈0.05）. After six months of treatment, efficacy evaluation was implemented, sputum negative rate of control group was 69.6%, the study group was 89.1% of sputum negative, the difference was statistically significant（P〈0.05）. There were no serious adverse reactions in the course of treatment. Conclusion For bronchial tuberculosis（TB）, treatment by bronchoscope in freezing method curative effect is better, can effectively improve the clinical symptoms, and relatively safe, is worth popularization in clinic.