胆道Cajal样间质细胞的研究进展

Updates of interstitial Cajal-like cell of biliary tract

Cajal问质细胞是位于胃肠道肌群的一种特殊间质细胞，其与平滑肌细胞，神经元细胞有密切联系，参与胃肠道的蠕动和神经信号传导，是胃肠道慢波的起搏细胞。存在于胆道、尿道、膀胱等胃肠道外器官的Cajal间质细胞被命名为Cajal样间质细胞（ICLC），笔者就ICLC在胆道系统的形态、鉴别、分类、功能、分布及其与胆道系统疾病的关系等方面作一综述。

Interstitial cell of Cajal （ICC） is a kind of special interstitial cell in the gastrointestinal tract, which has close connection with the smooth muscle cells and neuron cells. It is involved in gastrointestinal motility and nerve signal trans- duction and is considered as the pacemaker cell of slow wave of gastrointestinal tract. ICC which exists in the non-gastrointestinal organs such as biliary tract, urethra, bladder and so on is named interstitial Cajal-like cell （ICLC）. This article will review the progress in the research of ICLC in the biliary system in terms of their morphology, identification, classification, function, distri- bution and related biliary diseases.