探讨毛细式液基细胞学薄层染色技术对宫颈癌筛查应用价值研究

Sutdy on the Application Value of the Capillary Liquid- based Cytology Thin Layer Staining Technique(TCT) in the Screening of Cervical Cancer

目的探讨毛细式液基细胞学薄层染色技术(TCT)对宫颈癌筛查的临床应用价值。方法随机选取2011年6月—2013年7月期间在该院行宫颈癌筛查的患者480例,所有患者均行TCT检查,将其中意义不明确的不典型鳞状上皮细胞(ASCUS)以上病变视为阳性病变,并对其进行阴道镜活检,将活检结果和细胞学检测结果进行对比分析。结果 480例患者中,共计得到102例阳性标本,阳性率为21.25%;其中35例异常者的TCT检查的同阴道镜活检的符合率为88.57%。结论在宫颈癌筛查中应用毛细式液基细胞学薄层染色检查,可有效提高筛查质量,对于宫颈癌的预防和治疗具有十分重要的意义。

Objective To discuss the clinical application value of the capillary liquid- based cytology thin layer staining technique（TCT） in the screening of cervical cancer. Methods 480 cases of patients undergoing cervical cancer screening in our hospital from June 2011 to July 2013 were randomly selected and were given TCT examination, the equivocal atypical squamous epithelial cells（ASCUS） or above were regarded as the positive lesions and they were given the biopsy by colposcopy, and the biopsy results and cytological test results were compared and analyzed. Results There were 102 positive specimens of the 480 cases of patients, and the positive rate was 21.25%; the coincidence rate of TCT examination and biopsy by colposcopy of the 35 cases abnormal was 88.57%. Conclusion Capillary liquid- based cytology thin layer staining technique（TCT） in the screening of cervical cancer can effectively improve the screening quality, which is of important significance to the prevention and treatment of cervical cancer.