急性重症脑出血患者胰岛素强化治疗的临床研究

Clinical Research on the Intensive Insulin Therapy for Patients with Acute Severe Intracerebral Hemorrhage

目的探讨重症急性脑出血病人进行胰岛素强化疗法的临床效果。方法临床纳入60例该院2011年5月—2012年5月期间收治的急性重症脑出血患者,根据病人用药的不同分为对照组及观察组,每组30例,其中对照组服用降糖药基础疗法,观察组在上述基础上予以胰岛素强化疗法,评估两组病人治疗后GOS评分、肺炎发生率、生存情况。结果两组病人治疗后,病情均有所改善,观察组的医源性肺炎发生率为66.7%、对照组的医源性肺炎发生率为90.0%;观察组的生存率为93.3%,对照组的生存率为66.7%,差异有统计学意义(P<0.05);观察组治疗后的NIHSS评分及GOS评分情况显著优于对照组(P<0.05)。结论重症急性脑出血病人予以胰岛素强化疗法,可显著提高生存质量,降低并发症的发生,效果显著,值得临床推广。

Objective To discuss the clinical effect observation of the intensive insulin therapy for patients with acute severe intracerebral hemorrhage. Methods 60 cases of patients with acute severe intracerebral hemorrhage treated in our hospital from May 2011 to May 2012 were divided into two groups with 30 cases in each according to the different medications, the control group were given hypoglycaemic agents basic therapy, the observation group were given intensive insulin therapy on the basis of the control group, the GOS score, incidence of pneumonia and survival condition of the two groups after treatment were evaluated. Results The patient＇s condition of the two groups was improved after treatment, the incidence of nosocomial pneumonia was 66.7% in the observation group and 90.0% in the control group, the survival rate was 93.3% in the observation group and 66.7% in the control group, the differences were statistically significant（P〈0.05）,the NIHSS score and GOS score in the observation group were better than those in the control group after treatment,（P〈0.05）. Conclusion The intensive insulin therapy for patients with acute severe intracerebral hemorrhage can obviously improve the life quality, reduce the incidence of complications and has an obvious effect, and it is worth promoting.