甘露醇、能量合剂联合抗癫痫药治疗发作频繁的小儿难治性癫痫的疗效

Mannitol,energy mixture with antiepileptic drug therapy attacks frequently the curative effect of children with intractable epilepsy

目的：有效缓解小儿难治性癫痫发病症状,临床探究在使用抗癫痫药治疗同时加以甘露醇、能量合剂的效果。方法：选取我院2014年7月~2015年8月96例经诊断为难治性癫痫入院治疗的小儿患者,分为单一组、联合组,按挂号单双数进行分配,每组48例。单一组仅使用抗癫痫药,联合组在单一组用药基础上加用能量合剂以及甘露醇,观察两组疗效以及治疗前后发病次数。结果：联合组临床有效率高达91.7%,单一组仅为79.2%,联合组较单一组疗效好,P〈0.05;治疗前两组癫痫发病次数差异无统计学意义,P〉0.05,治疗后两组发病次数均有明显减少,联合组较单一组发病次数少,P〈0.05。结论：临床在治疗小儿难治性癫痫时在使用抗癫痫药同时加以甘露醇、能量合剂辅助治疗,患儿发病次数减少,恢复情况好,疗效高。

Objective：to effectively alleviate the symptoms in patients with refractory epilepsy children,in the use of antiepileptic drugs for clinical inquiry at the same time,the effect of mannitol and energy mixture. Methods：select our hospital during 2014.7~2015.8,96 cases diagnosed as intractable epilepsy hospitalized pediatric patients,divided into a single group,the joint group,according to the registered number of single and double,48 cases in each group. A single set of only the use of antiepileptic drugs,joint group on the basis of a single set of drug use and with energy mixture and mannitol,observe two groups of curative effect and the number of before and after treatment. Joint group clinical efficiency is as high as 91.7% as a result,a single set of only 79.2%,joint good curative effect in the single group,P 0.05; Two groups before treatment epilepsy frequency difference is meaningless,P 0.05,the number of two groups were significantly reduced after treatment,and less than the number of a single set of joint group,P0.05. Conclusion：clinical pediatric patients in the treatment of refractory epilepsy in the use of antiepileptic drugs to mannitol,energy mixture adjuvant therapy at the same time,the number of patients decreased,the recovery is good,high curative effect.