乙型肝炎病毒感染与肾功能损伤

HBV infection and kidney injury

长期乙型肝炎病毒（ HBV ）感染不仅能够引起肝脏损伤，而且对患者肾脏功能也会产生影响。慢性HBV感染相关的肾功能损伤，主要包括：（1）HBV相关性肾炎；（2）肝肾综合征；（3）长期口服核苷（酸）类药物导致的肾功能损伤。该文主要介绍了HBV感染引起肾功能损伤的发病机制及其治疗原则，以期为进一步指导临床治疗提供基础。

Chronic HBV infection may not only cause liver damage , but also lead to renal injury . HBV-related kidney injuries mainly include （ 1 ） HBV-associated glomerulonephritis , （ 2 ） hepatorenal syndrome, and （3） kidney injuries caused by long-term nucleos（t）ide analogues therapy.This paper mainly reviews the pathogenesis and therapeutic principle of HBV-related kidney injuries , so as to provide the foundation for clinical management .