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超敏-C反应蛋白水平对体外受精-胚胎移植妊娠结局的影响

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摘要 目的探讨体外受精-胚胎移植(IVF-ET)患者血清超敏C反应蛋白(hs-CRP)水平变化与妊娠结局的关系。方法选择180例行IVF-ET治疗的患者,根据妊娠结局分为非妊娠组(n=78)和临床妊娠组(n=102),分别检测其启动日、人体绒膜促性腺激素(HCG)日、取卵日和胚胎移植日血清hs-CRP浓度。结果临床妊娠组的不孕年限小于未妊娠组(P<0.05)。临床妊娠组启动日hs-CRP水平低于未妊娠组,但差异无统计学意义(P>0.05);与本组启动日比较,临床妊娠组的HCG日、取卵日和胚胎移植日hs-CRP水平均显著升高,差异有统计学意义(P<0.05);临床妊娠组HCG日、取卵日和胚胎移植日hs-CRP水平显著高于未妊娠组,差异有统计学意义(P<0.05)。结论经过控制性超排卵,血清hs-CRP浓度明显升高,提示控制性超排卵有潜在全身的炎症反应,一定程度的hs-CRP水平升高有助于IVF患者成功妊娠。
出处 《中国初级卫生保健》 2016年第4期29-30,共2页 Chinese Primary Health Care
基金 广东省医学科研基金课题(A2013638) 中国高校医学期刊临床专项资金(11525520)
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参考文献10

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