摘要
目的 探讨不同透析方式治疗尿毒症患者的临床疗效。方法整群选择2013年5月—2015年5月期间该院收治的114例尿毒症患者作为研究对象,根据随机数字表将其平均分为HD组、HD+HP组与HDF组,每组38例。结果3组治疗后Scr、Pi、BUN均较治疗前明显降低,但3组间对比差异均无统计学意义(P>0.05)。经相应治疗后,HD+HP组与HDF组β2-MG、PTH及Cys C参数均低于HD组(P<0.05);HD+HP组与HDF组β2-MG、PTH及Cys C参数对比差异无统计学意义(P>0.05)。结论 HD、HDF与HD+HP对于小分子物质的清除效果基本相同,而HDF与HD+HP对中、大分子物质的清除作用却优于单纯HD,可作为尿毒症首选治疗方案,适于临床推广。
Objective To investigate the clinical effect of different methods of dialysis in treating uremic patients. Methods114 cases with uraemia admitted in our hospital from May 2013 to May 2015 were selected as the subjects and randomly divided into HD group（hematodialysis）, HD＋HP group（hematodialysis and hemoperfusion） and HDF group（hematodialysis and hemofiltration）, 38 cases in each group. Results Scr, Pi and BUN all obviously reduced after treatment. The difference in Scr, Pi and BUN between three groups had no statistical significance（P〈0.05）. After treatment, the β2-MG, PTH and Cys C in HD＋HP group and HDF group were lower than in HD group（P〈0.05）. The difference in β2-MG, PTH and Cys C between HD＋HP group and HDF group had no statistical significance（P0.05）. Conclusion HD, HDF and HD＋HP have essentially the same effect on clearing small molecule material. The effect of HDF and HD＋HP on clearing the medium and macromolecule material was obviously better than HD, so it can be used as the first therapy for uraemia and is suitable for clinical promotion.
出处
《中外医疗》
2016年第7期18-20,共3页
China & Foreign Medical Treatment
