复方聚乙二醇电解质散在妇科术前肠道准备中舒适度的影响及对策

Effect of Polyethylene Glycol Electrolyte Powder Applied to the Preoperative Bowel Preparation for Gynecological Surgery on the Degree of Comfort and the Countermeasures

目的探讨复方聚乙二醇电解质散3种方法口服对妇科术前肠道准备患者舒适度的影响。方法整群选取2012年12月—2013年7月在该院妇科接受手术治疗的166例腹腔镜手术患者,随机分为3组,A组(53例)术前1 d 19:30口服复方聚乙二醇电解质散2盒,B组(56例)术前1 d 16:00服药2盒,C组(57例)分别于术前1 d 16:00和19:30各服药1盒。根据患者服药中和服药后不良反应及舒适度评价。结果 3组服药不良反应和舒适度比较,差异无统计学意义(P﹥0.05)。但不良反应发生率:服药后的44.6%(74例)明显高于服药过程中的29.5%(49例),主要不良反应表现为恶心、胃部不适、口感差、头晕。结论药物不良反应发生率越高舒适度越低,应加强口服复方聚乙二醇电解质散患者的用药指导,积极缓解不适,提高患者服药的舒适性和肠道清洁效果。

Objective To study the effect of Polyethylene Glycol Electrolyte Powder administered orally by 3 Methods for the preoperative bowel preparation on the degree of comfort in patients with gynecological surgery. Methods 166 patients underwent surgery in Department of Gynecology of our hospital from December 2012 to July 2013 were randomly divided into 3 groups, group A（53 cases）, group B（56 cases）, and group C（57 cases）. Group A and Group B respectively orally took two packs of Polyethylene Glycol Electrolyte Powder at 19：30 pm, 16：00 pm 1 d before the gynecologic surgery. Group C orally took 1 pack of Polyethylene Glycol Electrolyte Powder at 16：00 pm and 19：30 pm, respectively 1 d before the gynecologic surgery. The evaluations are made according to the degree of comfort and side effects during and after the medication. Results The difference in the incidence of side effects and degree of comfort between the 3 groups was not statistically significant（P〈0.05）. The incidence of side effects after medication was much higher than that during medication [44.6 %（74cases） vs 29.5%（49 cases）]. The major side effects were nausea, stomach discomfort, bad palatability and dizziness. Conclusion The degree of comfort decreases with the increase of the incidence of side effects, so the medication instruction of Polyethylene Glycol Electrolyte Powder should be strengthened in order to reduce the discomfort, improve the degree of comfort and effect of bowel cleaning.