微波消解-电感耦合等离子体质谱法测定保健食品中的9种元素

Determination of 9 kinds of elements in health food by microwave digestion-inductively coupled plasma mass spectrometry

目的建立微波消解-电感耦合等离子体质谱法检测液体水基、固体粉基、软胶囊基3种基质的保健食品中钠、镁、钾、钙、锰、铁、铜、锌、硒9种元素的分析方法。方法前处理方法采用硝酸-双氧水体系的微波消解法,仪器检测方法采用电感耦合等离子体质谱法。对3种基质的保健食品中9种元素进行同时测定。通过在线加入标准溶液实现对样品的实时校正,内标为^(103)Rh和^(185)Re。结果方法的线性范围宽,跨越两个数量级;9种元素相关系数r均在0.999以上;检出限低;9种元素回收率在82%~120%之间;精密度在7.8%以内。结论本方法准确、灵敏、简便,适合进行液体水基、固体粉基、软胶囊基3种基质的保健食品中钠、镁、钾、钙、锰、铁、铜、锌、硒9种元素的同时测定。

Objective To establish a method for simultaneous determination of 9 kinds of elements such as Na,Mg,K,Ca,Mn,Fe,Cu,Zn,and Se,in liquid,solid,and soft capsule types of health food by microwave digestion- inductively coupled plasma mass spectrometry（ICP-MS）.Methods Nine kinds of elements in 3 kinds of matrix of health food were firstly decomposed by microwave oven with nitric acid and hydrogen peroxide,and then determined simultaneously by ICP-MS.Samples were corrected by adding internal standard solution on line,with ^（103）Rh and ^（185）Re as internal standard.Results This method showed a wide linearity range,and low detection limit.The recoveries were in the range of 82%~120%,and relative standard deviations were under 7.8%.Conclusion This method is rapid,sensitive and accurate,and suitable for the simultaneous determination of Na,Mg,K,Ca,Mn,Fe,Cu,Zn,and Se in 3 kinds of matrix of liquid,solid and soft capsule.