摘要
目的评价不同系统上检测的PCT结果的相关性及其在临床应用上的符合性。方法留取在梅里埃VIDAS免疫分析仪上检测浓度在0 ng/ml^200 ng/ml的PCT样本,按不同浓度依次分为1组(0.05 ng/ml^0.50 ng/ml)、2组(0.51 ng/ml^2.00 ng/ml)、3组(2.01 ng/ml^10.00 ng/ml)、4组(>10.00 ng/ml),在美国睿捷Nano-Checker 710免疫层析检测仪上检测PCT。并对两者检测的结果进行相关性和临床应用符合性分析。结果 2台仪器检测的数据总体具有良好的相关性(r=0.961 6),临床应用意义整体符合度为96%(48/50)。在低浓度1组和高浓度4组中,2台仪器的检测结果均具有良好的相关性(r值分别为0.866、0.983)和较高的临床应用意义的符合度(94.11%、100%);在中间浓度的2组和3组,尽管相关系数较低(r值分别为0.389、0.242),但具有较高的临床应用意义符合度(100%、90%)。结论 2台仪器上测量的PCT结果对临床具有相同的应用价值。
Objective To evaluate the correlation of the test results with different detection systems for serum procalcitonin( PCT) and the consistency in clinical application. Methods PCT samples with concentration range at 0 ng/ml- 200 ng/ml by Bio Mérieux VIDAS mini Immunoassay Analyzer were collected,which were also detected with Nano- Checker 710 Immune Chromatography Analyzer,and divided into four groups according to the different concentration: group 1( 0. 05 ng / ml- 0. 50 ng / ml);group 2( 0. 51 ng / ml- 2. 00 ng / ml); group 3( 2. 01 ng / ml- 10. 00 ng / ml); group 4( 10. 00 ng / ml). The results with two detection systems were analyzed on the correlation and compliance of clinical application. Results Data with two detection systems generally had a good correlation( r = 0. 961 6). Conformity degree in clinical application was 96%( 48 /50). In the low concentration group 1 and high concentration group 4,the detection results of the 2 instruments had a good correlation( r =0. 866,0. 983) and higher conformity with clinical significance( 94. 11%,100%); in the intermediate concentration group 2and group 3,although the correlation coefficient was low( r = 0. 389,0. 242),they had a higher consistency with clinical application significance( 100%,90%). Conclusion The test results of PCT showed significance on clinical application between the two detection systems.
出处
《中国卫生检验杂志》
CAS
2016年第7期1000-1002,共3页
Chinese Journal of Health Laboratory Technology
关键词
降钙素原
不同系统
相关性
临床应用符合性
Procalcitonin
Different systems
Correlation
Consistency of clinical application