北京朝阳区2011年-2014年麻疹疑似病例实验室检测结果分析

Analysis of laboratory test results of suspected measles cases in Chaoyang district of Beijing during 2011-2014

目的分析北京市朝阳区麻疹疑似病例血清学检测情况,为麻疹的防控提供科学依据。方法采用酶联免疫法（ELISA）对北京市朝阳区2011年-2014年麻疹疑似病例血清标本进行麻疹和风疹Ig M抗体检测,对检测结果按照不同人群进行统计分析。结果 843例疑似病例中,麻疹Ig M抗体阳性244例,阳性率为28.94%（244/843）;风疹Ig M抗体阳性187例,阳性率为22.18%（187/843）。麻疹、风疹病例性别分布差异无统计学意义。麻疹和风疹发病主要分布在15岁-39岁,且发病时间主要集中在第2季度,同时外地病例为发病主体。结论加强青壮年的免疫规划是今后工作中需要重视的一点,应进一步开展查漏补种和强化免疫工作,提高易感人群的免疫水平,并加强托幼机构、学校和集中办公场所的区域消毒,最终达到控制和消除麻疹流行的目的。

Objective To analyze the serological test results of suspected measles cases in Chaoyang district of Beijing,so as to provide scientific basis for the prevention and control of measles. Methods Using enzyme linked immunosorbent assay（ ELISA）,to conduct measles and rubella Ig M antibody test on the suspected measles cases in Chaoyang district of Beijing during 2011- 2014,and statistical analysis was conducted among different groups according to the test results. Results 244 cases showed measles Ig M antibody positive in 843 suspected measles cases,the positive rate was 28. 94%（ 244 /843）; and 187 cases showed rubella Ig M antibody positive,and the positive rate was 22. 18%（ 187 /843）. There was no statistical significance on the difference of gender distribution for measles and rubella cases. Measles and rubella mainly happen in 15- 39 years old group in the second quarter. Most cases were imported from elsewhere. Conclusion The focus of our future work is to strengthen the immune planning management in young adults,enhance the immunity levels of susceptible population,intensify the nurseries,schools and office sites area disinfected,so as to ultimately achieve the control and elimination of measles.