低强度脉冲超声波治疗新鲜下肢骨骨折的病例对照研究

Case-control Study of the Low-intensity Pulsed Ultrasound Treatment for Fresh Diaphyseal Fractures of the Lower Limbs

目的研究低强度脉冲超声(low-intensity pulsed ultrasound,LIPUS)促进新鲜下肢骨骨折愈合的作用。方法采用病例对照的研究方法,根据是否使用LIPUS治疗将99例新鲜下肢骨骨折患者分为LIPUS治疗组和对照组。术后LIPUS治疗组每日治疗15 min,对照组仅用石膏托固定。对LIPUS治疗组与对照组骨折愈合时间进行总体比较,并对骨折侧位、骨折位置、骨折类型、软组织损伤类型及外科治疗方式下的亚组结果进行分析比较。结果 LIPUS治疗组骨折部位的平均愈合时间为(4.44±2.19)个月,短于对照组的平均愈合时间(5.04±2.96)个月,但组间差异无统计学意义(P>0.05)。粉碎性骨折患者经LIPUS治疗后平均愈合时间为(4.73±2.25)个月,显著短于对照组的(6.73±2.37)个月(P=0.025)。结论 LIPUS能够有效地促进术后新鲜下肢骨粉碎性骨折的愈合。

Objective To investigate the effects of low-intensity pulsed ultrasound（ LIPUS） treatment for fresh diaphyseal fractures of the lower limbs. Methods A case-control study was performed in 99 fresh diaphyseal fractures of the lower limbs patients. All subjects were divided into the LIPUS group and the control group according to the treatment choice of LIPUS. After operation,the LIPUS group were immobilized by plaster and received LIPUS for 15 min daily,and the control group were only immobilized by plaster. An overall comparison was performed between the LIPUS group and the control group,as well as subgroup analysis in items of the fracture lateral,fracture sites,fracture types,soft tissue conditions,and fixation methods between the groups. Results The average fracture healing time of LIPUS group was（ 4. 44 ± 2. 19） months,and the control group was（ 5. 04 ± 2. 96） months. There was no statistically significant difference between the two groups.Clinical fracture-healing time of comminuted fracture in LIPUS group was（ 4. 73 ± 2. 25） months,which was significantly shorter than that in control group,（ 6. 73 ± 2. 37） months（ P = 0. 025）. Conclusion LIPUS is effective for surgically managed,fresh,comminuted fracture healing of the lower limbs.