小金胶囊治疗甲状腺结节临床研究

Clinical Observation of Xiaojin Capsule in the Treatment of Nodular Goiter

目的:观察小金胶囊治疗甲状腺结节的临床疗效及作用机制。方法:将80例符合甲状腺结节诊断标准的患者随机分为2组。对照组40例,给予优甲乐口服治疗。治疗组40例,给予小金胶囊口服。2组连续治疗3个月后观察治疗前后有效率及甲状腺功能的变化。结果:治疗组临床总有效率明显高于对照组(P<0.05)。2组治疗后FT3、FT4无明显变化(P>0.05)。治疗组治疗后s TSH无明显变化(P>0.05),对照组治疗后s TSH明显降低(P<0.05)。结论:小金胶囊治疗甲状腺结节疗效显著,值得临床推广应用。

Objective：To observe the clinical effect and the mechanism of Xiaojin capsule on nodular goiter. Methods：Eighty ca- ses of nodular goiter in accordance with diagnostic criteria were randomized into 2 groups. The control group （40 patients） was treated with euthyrox and the treatment group with Xiaojin capsule. The efficacy was observed after 3 months in both of the groups. Results：The total effective rate of treatment group was higher than that of the control group（P 〈0. 05）. FT3 and FT4 in the two groups showed no significant difference（P 〉 0. 05 ）. sTSH level of the observation was not improved （P 〉 0. 05 ） while sTSH level of control group was significantly reduced than before treatment. The difference has statistical difference（P 〈 0. 05 ）. Conclusion： Xiaojin capsule has obvious clinical effect on treating nodular goiter, and it is worth of promotion.