药物利用研究在中药注射剂临床应用合理性和安全性评价中的应用

Drug utilization research on rationality and safety of TCM injections on clinic

随着中药注射剂上市后再评价的深入,围绕着中药注射剂安全性、有效性、经济性的评价,开展了大量的探讨。作为中药注射剂安全和有效使用的基础,合理用药也是中药注射剂上市后再评价研究不可忽视的重要研究内容。采用药物利用研究的相关方法对中药注射剂在医疗机构中的使用进行评价,不仅能够进一步的指导临床用药,提供合理用药信息,还可以促进医院的药事管理,同时药物利用研究具有的经济学评价属性使得其可以为医政部门制定药品政策提供决策依据。通过对中药注射剂的药物利用研究,提示基于PDD计量指标的药物利用研究可作为中药注射剂药物利用评价的借鉴方法,基于DUR的药物流行病学和药物经济学能够为中药注射剂临床使用合理性与安全性再评价提供可借鉴的思路和方法。

With the traditional Chinese medicine injection listed after the evaluation of in-depth,around traditional Chinese medicine injection safety,effectiveness,economic evaluation,carried out a lot of discussion. As the basis of traditional Chinese medicine injection safety and effective use,rational use of drugs of TCM injections also listed after the evaluation study cannot be ignore research. Methods related to study drug use in TCM injections use in medical institutions were evaluated,not only to further clinical medicine,provide rational drug information,but also promote the hospital＇s pharmacy management,drug utilization has also studied economics evaluation property so that it can develop drugs policy is medical affairs departments to provide basis for decision making. TCM injections by drug use study,suggesting the study drug use based on measurable indicators PDD can be used as traditional Chinese medicine injection drug utilization evaluation reference method,based on Pharmacoepidemiology and Pharmacoeconomics DUR can use rationality and safety of TCM injections clinical re-evaluation to provide ideas and methods for reference.