类鼻疽特异性抗原和壁膜抗原对金黄地鼠和家兔的保护性研究

Study on Protective Effect of Specific Antigen and Cell Wall-membrane Antigen of Pseudomonase Pseudomallei to Anrmals

本实验用类鼻疽特异抗原和壁膜抗原分别免疫金黄地鼠和家兔,然后攻击金黄地鼠,观察家兔腹腔巨噬细胞对细菌的吞噬作用。实验证明这两种抗原具有刺激机体产生免疫保护的作用,吞噬能力的增强是免疫保护的一个因素,吞噬能力不依赖于抗体产生的水平。

This experiment proved that specific antigen and cell wall-membrane antigen of P. pseudomallei were able to stimulate organisms to product immune protection. Phagocytosis took an important role in the immune protection. Phagocytosis was not related with serum titre in body.