化疗期肺癌患者应对方式与胃肠道反应的相关性

Correlation of coping styles with gastrointestinal reaction in patients with lung cancer on chemotherapy

目的探讨化疗期肺癌患者应对方式与胃肠道反应的相关性。方法对120例化疗期肺癌患者分别采用一般情况调查表、医学应对问卷、胃肠道反应评估表进行调查,并对结果进行分析。结果除回避得分与便秘得分、屈服得分与腹泻得分的相关性无统计学意义(P>0.05)外,面对、回避得分与患者胃肠反应得分均呈负相关(r值范围-0.419^-0.150,P<0.05),而屈服得分与患者胃肠反应得分均呈正相关(r值范围0.156~0.375,P<0.05)。进一步多元线性逐步回归分析发现,面对和屈服对患者胃肠道反应的影响有统计学意义(P<0.05),分别可解释相应胃肠道反应9.9%~21.9%的变异,屈服对其影响为正性,而面对为负性。结论应对方式与化疗期肺癌患者胃肠道反应密切相关,患者积极地应对有助于减轻胃肠道反应。

Objective To investigate the correlation of coping styles with gastrointestinal reaction in patients with lung cancer on chemotherapy in order to provide data for clinical intervention study. Methods 120 cases of lung cancer patients on chemotherapy were investigated by the general questionnaire,Medical Coping Modes Questionnaire and gastrointestinal reaction assessment form. The results were analyzed. Results Scores of face and avoidance were negatively correlated with score of gastrointestinal reactions（ r value ranged from- 0. 419 to- 0. 150,P〈0. 05）,while score of yield was positively correlated with score of gastrointestinal reactions（ r value ranged from 0. 156 to 0. 375,P〈0. 05）. There was no correlation between scores of avoidance and constipation,and between scores of yield and diarrhea（ P〉0. 05）.Multivariate linear stepwise regression analysis showed that the effects of face and avoidance on gastrointestinal reaction were statistically significant（ P〈0. 05）,which could explain the variation of 9. 9%- 21. 9% of the gastrointestinal reaction. The effect of yield was positive,but the effect of face was negative. Conclusion Coping styles is closely related to the gastrointestinal reaction in patients with lung cancer on chemotherapy,and positive coping styles can help to reduce gastrointestinal reactions.