期刊文献+

艾滋病病人淋巴细胞计数对肺孢子菌肺炎的预测分析 被引量:1

Prediction analysis of lymphocyte count in patients with AIDS on pneumocystis pneumonia
下载PDF
导出
摘要 [目的]探讨艾滋病病人淋巴细胞绝对计数(ALC)对肺孢子菌肺炎(PCP)的预测价值。[方法]选择55例合并PCP和49例不合并PCP艾滋病病人作为研究对象,分析ALC计数与CD_4^+T细胞的相关性,比较ALC计数与CD_4^+T细胞在是否合并PCP病人间表达的差异。[结果]艾滋病病人ALC计数与CD_4^+T细胞计数呈正相关(r=0.618,P=0.000);合并PCP艾滋病病人与未合并PCP病人ALC表达水平比较差异有统计学意义(P=0.002);合并PCP艾滋病病人与未合并PCP病人CD_4^+T细胞计数表达水平比较差异有统计学意义(P=0.000);ALC计数及CD_4^+T细胞预测PCP的ROC曲线下面积分别为(0.701±0.053)、(0.784±0.045),两者比较差异无统计学意义(P=0.233);CD_4^+T细胞计数最佳预测值30.8个/μL、ALC计数最佳预测值1 100.0个/μL是预测PCP发生的较好指标。[结论]ALC计数及CD_4^+T细胞预测PCP发生有同等预测价值,急诊艾滋病病人检测ALC对引起肺部炎症病原体的初步判断有一定的参考意义。
出处 《护理研究(下旬版)》 2016年第3期1089-1091,共3页 Chinese Nursing Researsh
基金 南通市卫生局青年基金项目 编号:WQ2014035
  • 相关文献

参考文献10

  • 1StringerJR,BeardCB,MillerRF,etal.Anewname(pneumocystisjiroveci)forpneumocystisfromhumans[J].EmergInfectDis,2002,8(9):891-896.
  • 2ThomasJrCF,LimperAH.Pneumocystispneumonia[J].NEnglJMed,2004,350(24):2487-2498.
  • 3NapoliAM,FischerCM,PinesJM,etal.Absolutelymphocytecountintheemergencydepartmentpredictsalow-CD4countinadmittedHIV-positivepatients[J].AcadEmerg-Med,2011,18(4):385-389.
  • 4中华医学会感染病学分会艾滋病学组.艾滋病诊疗指南(2011版)[J].中华传染病杂志,2011,29:629-640.
  • 5KaplanJE,BensonC,HolmesKK,etal.GuidelinesforpreventionandtreatmentofopportunisticinfectionsinHIV-infectedadultsandadolescents:recommendationsfrom-CDC,theNationalInstitutesofHealth,andtheHIV-MedicineAssociationoftheInfectiousDiseasesSocietyofAmerica[J].MMWR-Recomm-Rep,2009,58(RR-4):1-207.
  • 6NapoliAM,MaughanB,MurrayR,etal.UseoftherelationshipbetweenabsolutelymphocytecountandCD4counttoimproveearlierconsiderationofpneumocystispneumoniainHIVpositiveemergencydepartmentpatientswithpneumonia[J].JEmergMed,2013,44(1):28-35.
  • 7MwamburiDM,GhoshM,FauntleroyJ,etal.PredictingCD4countusingtotallymphocytecount:asustainabletoolforclinicaldecisionsduringHAARTuse[J].AmJTropMedHyg,2005,73(1):58-62.
  • 8SchurmannM,SchurmannD,SchindlerR,etal.ImpairedthymicfunctionandCD4+Tlymphopenia,butnotmannose-bindinglectindeficiency,areriskfactorsforPneumocystisjiroveciipneumoniainkidneytransplantrecipients[J].TransplImmunol,2013,28(4):159-163.
  • 9PereiraRM,MullerAL,ZimermanRA,etal.HighprevalenceofpneumocystisjirovecicolonizationamongHIV-positivepatientsinsouthernBrazil[J].MedMycol,2014,52(8):804-809.
  • 10RieboldD,EnohDO,KingeTN,etal.PneumocystisjirovecicolonisationinHIVpositiveandHIV-negativesubjectsinCameroon[J].TropMedIntHealth,2014,19(6):643-655.

共引文献12

同被引文献14

引证文献1

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部