2型糖尿病患者如何选择中预混和低预混胰岛素类似物

How to choose mid-premixed and low-premixed insulin analogue for patients with type 2 diabetes

糖尿病已成为严重威胁健康的主要慢性疾病之一。中国糖尿病患者数居全球首位,目前2型糖尿病(T2DM)患者呈现出以餐后血糖升高为主,胰岛素敏感性降低和胰岛β细胞功能减退的特点。预混胰岛素类似物根据自身的特点分为中预混和低预混胰岛素,且应用灵活方便,低血糖风险低,更加安全,为2型糖尿病患者带来了新的选择和希望。

Diabetes has become one of the major chronic diseases in the world that is a serious threat to the health of people. The number of Chinese patients with diabetes ranks first in the whole world. Now patients with type 2 diabetes mellitus（T2DM） are primarily characterized as the rise in blood sugar after meals, the decrease of insulin sensitivity and the attenuation of β cell function. Premixed insulin analogs can be divided into mid-premixed or low- premixed insulin based on its own characteristics and can be conveniently applied with lower risk of hypoglycemia and higher safety, which can bring in new choice and hope for patients with type 2 diabetes.