恶性胸腔积液患者应用卡铂腔内治疗的效果分析

Efficacy of Carboplatin Cavity in the Treatment of Patients With Malignant Pleural Effusion

目的分析恶性胸腔积液患者应用卡铂腔内治疗的临床效果。方法选择2013年1月~2014年12月我院收治的76例恶性胸腔积液患者作为研究对象,随机将患者分成对照组与观察组。对照组应用常规治疗,观察组应用卡铂腔内治疗,比较两组生活质量、毒副反应、近期疗效等情况。结果观察组生活质量、近期疗效高于对照组,差异具有统计学意义（P〈0.05）;两组毒副反应对比,差异不具有统计学意义（P〉0.05）。结论应用卡铂腔内治疗恶性胸腔积液患者可以改善患者生活质量,减少毒副反应,提高近期疗效。

Objective To analyze efficacy of carboplatin cavity in the treatment of patients with malignant pleural effusion. Methods We selected 78 cases with malignant pleural effusion as study objects admitted in our hospital from January 2013 to December 2014. They were randomly divided into control group and observation group. The former adopted conventional treatment while the latter used carboplatin endovascular treatment. At last, we compared their living quality, toxic and side, short-term curative effect and so on. Results The quality of life and short-term effect in the observation groupnd were significantly higher than the control group, which had statistical significance（P0.05）. But the two groups＇ toxic and side effect had no statistical significance（P0.05）. Conclusion Endovascular treatment with carboplatin in patients with malignant pleural effusion can improve the quality of life of patients and reduce toxicity and improve the short-term effect.